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Obestatin (human)

CAS No. 1081110-72-6

Obestatin (human)( —— )

Catalog No. M35043 CAS No. 1081110-72-6

Obestatin (human) is an endogenous ligand for G-protein eurythmic entity 39 formed by shearing of preproghrelin, which inhibits feeding in a dose-dependent manner, and can be used in the study of obesity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 196 Get Quote
5MG 376 Get Quote
10MG 566 Get Quote
25MG 858 Get Quote
50MG 1150 Get Quote
100MG 1521 Get Quote
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Biological Information

  • Product Name
    Obestatin (human)
  • Note
    Research use only, not for human use.
  • Brief Description
    Obestatin (human) is an endogenous ligand for G-protein eurythmic entity 39 formed by shearing of preproghrelin, which inhibits feeding in a dose-dependent manner, and can be used in the study of obesity.
  • Description
    Obestatin(human) is a 23-amino acid amidated peptide that regulates appetite and gastrointestinal motility via its interaction with GPR39. Obestatin(human) can be used for weight loss. Obestatin(human) cannot penetrate the cell membrane.
  • In Vitro
    The primary structure of Obestatin(human) indicates that it only presented one lysine at position 10, which suggests that it cannot penetrate the cell membrane.
  • In Vivo
    In adult male mice, intraperitoneal injection of Obestatin(human) suppresses food intake in a timeand dose-dependent manner.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1081110-72-6
  • Formula Weight
    2546.83
  • Molecular Formula
    C116H176N32O33
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 1.96 mg/mL (0.77 mM; ultrasonic and adjust pH to 5 with HCl )
  • SMILES
    C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)C)=O)CCC(N)=O)=O)CO)=O)=O)CCC(N)=O)=O)CCC(N)=O)=O)=O)CCC(N)=O)=O)C(C)C)=O)=O)CO)=O)CC(C)C)=O)CCCCN)=O)[C@H](CC)C)=O)=O)[C@@H](C)C)=O)CC(O)=O)=O)(=O)[C@H]4N(C([C@@H](NC([C@@H](NC([C@H](CC5=CC=CC=C5)N)=O)CC(N)=O)=O)C)=O)CCC4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Guangcai Ren, et al. Effect of TAT-obestatin on proliferation, differentiation, apoptosis and lipolysis in 3T3-L1 preadipocytes. J Pept Sci. 2013 Nov;19(11):684-91.?
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